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SHP099 Size:5mg It is converted from 6-carboxytetramethylrhodamine

SKU: 5504729754

4.7
USD90.00 USD120.00

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Description

It is converted from 6-carboxytetramethylrhodamine (6-TAMRA) and has similar spectroscopic properties of 6-TAMRA

335 SMILES OCCCC#CC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

S)-AHPC-CO-C3-piperazine HCl Synonyms CAS Number n/a Related CAS Molecular Formula C30H46Cl2N6O4S Molecular Weight 657

Product Name Thalidomide-5'-propargyl-OH Synonyms CAS Number 1216805-32-1 Related CAS Molecular Formula C16H12N2O5 Molecular Weight 312

SHP099 Size:5mg It is converted from 6-carboxytetramethylrhodamineSHP099 is a highly potent (IC50 = 0. 071uM),selective and orally bioavailable small molecule SHP2 inhibitor. The inhibiting SHP2 activity of SHP099 is through an allosteric mechanism. SHP099 suppresses RASERK signalling to inhibit the proliferation of receptor tyrosine kinase driven human cancer cells in vitro and is efficacious in mouse tumour xenograft models. Product Name SHP099 Synonyms CAS Number 1801747 42 1 Related CAS Molecular Formula

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