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Unfortunately, the archetype is updated infrequently, so a deck based around the Synchron archetype can have many weaknesses, including anti-summoning effects, effects that work against low levels and low attack and defense points, and various negation effects

The next format is going to see HP powerhouses as well, so we should consider the fact that an extra 10 damage might not be worth it, especially with PlusPower still around

[Lightning][Colorless] Spark 50 This attack also does 20 damage to 1 of your opponent's Benched Pokemon

I think Thalia is actively good in this matchup, in contrast to how I think its poor against Orzhov